AUTHORS : Alepee N. Amsellem Carole Bertino Beatrice Bremond Christelle Capallere Christophe Cotovio J de Brugerolle de Fraissinette A. Grandidier MH Leclaire J Lee AV Lelièvre D Loisel-Joubert Sophie Maloug Saber Meunier Jean-Roch Minondo Anne-Marie Ovigne Jean-Marc Tinois-Tessonneaud Estelle MODELS : HCE / HUMAN CORNEAL EPITHELIUM APPLICATIONS : Eye irritation OCULAR IRRITATION OF CHEMICAL In vitro assessment of eye irritancy using the Reconstructed Human Corneal Epithelial SkinEthic HCE model: application to 435 substances from consumer products industry. 2010 Toxicology In Vitro. 2010 Mar;24(2):523-37. | L'Oréal, Research & Innovation
AUTHORS : Alepee N. Amsellem Carole de Brugerolle de Fraissinette A. Doucet O Meloni M Pachot Jean Robert C Roux Marie-Helene Tornier C MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS A catch-up validation study on reconstructed human epidermis (SkinEthic RHE) for full replacement of the Draize skin irritation test. 2010 Toxicology In Vitro. 2010 Feb;24(1):257-66 | L'Oréal, Research & Innovation
AUTHORS : Alepee N. Amsellem Carole de Brugerolle de Fraissinette A. Tornier C MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS Assessment of the optimized SkinEthic Reconstructed Human Epidermis (RHE) 42 bis skin irritation protocol over 39 test substances. 2010 Toxicology In Vitro. 2010 Feb;24(1):245-56 | SkinEthic
AUTHORS : Alepee N. Amsellem Carole de Brugerolle de Fraissinette A. Doucet O Meloni M Pachot Jean Robert C Roux Marie-Helene Tornier C MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN IRRITATION OF CHEMICALS A catch-up validation study on reconstructed human epidermis (SkinEthicTM RHE) for full replacement of the Draize skin irritation test 2009 | SkinEthic
AUTHORS : Alepee N. Amsellem Carole de Brugerolle de Fraissinette A. Tornier C MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN IRRITATION OF CHEMICALS Assessment of the optimized SkinEthicTM Reconstructed Human Epidermis (RHE) 2009 | SkinEthic
AUTHORS : Jessen Bart A. Khoh-Reiter Su MODELS : HCE / HUMAN CORNEAL EPITHELIUM Evaluation of the cytotoxic effects of ophthalmic solutions containing benzalkonium chloride on corneal epithelium using an organotypic 3-D model 2009 | SkinEthic
AUTHORS : Alepee N. Amsellem Carole Bertino Beatrice Bremond Christelle Capallere Christophe Cotovio J de Brugerolle de Fraissinette A. Grandidier M H Leclaire J Lelièvre D Loisel-Joubert Sophie Maloug Saber Meunier Jean-Roch Minondo Anne-Marie Ovigne Jean-Marc Tinois-Tessonneaud Estelle Van Der Lee Aline MODELS : HCE / HUMAN CORNEAL EPITHELIUM In vitro assessment of eye irritancy using the Reconstructed Human Corneal Epithelial SkinEthic™ HCE model: Application to 435 substances from consumer products industry 2009 | SkinEthic
AUTHORS : Baudouin Jean-Eric Bertino Beatrice Boulgana Rachid de Brugerolle de Fraissinette A Mahé Yann Sahuc F Samarsky Dmitry Sextius Peggy Tailor Peggy Teluob Séverine Welch Peter MODELS : RHPE / RECONSTRUCTED HUMAN PIGMENTED EPIDERMIS APPLICATIONS : PIGMENTATION Potential use of RNA i on human skin 2009 | SkinEthic, L'Oréal, Invitrogen, RXI Pharmaceuticals
AUTHORS : Duché Daniel Ferraris C Labrie Fernand Leclaire J Luu-The Van Meunier Jean-Roch MODELS : EPISKIN APPLICATIONS : SKIN METABOLISM Expression profiles of phases 1 and 2 metabolizing enzymes in human skin and the reconstructed skin models EpiskinTM and full thickness model from EpiskinTM 2009 Elsevier Journal of Steroid Biochemistry and Molecular Biology | L'Oréal, Episkin, SkinEthic
AUTHORS : Garrigues A. Gregoire S. Meunier Jean-Roch Patouillet C Wargniez W. MODELS : EPISKIN APPLICATIONS : PERCUTANEOUS ABSORPTION PROMISING ALTERNATIVE METHOD FOR SKIN PENETRATION EVALUATION USING RECONSTRUCTED EPIDERMIS MODEL 2009 | L'Oreal, Episkin, SkinEthic
AUTHORS : Baudouin Christophe De Servi Barbara Le Varlet Béatrice Meloni M Pauly Aude MODELS : HCE / HUMAN CORNEAL EPITHELIUM Occludin gene expression as an early in vitro sign for mild eye irritation assessment 2009 Elsevier Toxicology in vitro | Vitroscreen
AUTHORS : Baudouin Christophe Brignole-Baudouin Francoise Meloni M Pauly Aude Warnet Jean-Michel MODELS : HCE / HUMAN CORNEAL EPITHELIUM APPLICATIONS : PHARMACOLOGY / TOXICOLOGY Multiple Endpoint Analysis of the 3D-Reconstituted Corneal Epithelium after Treatment with Benzalkonium Chloride: Early Detection of Toxic Damage 2009 lnvestigative Ophtalmology & Visual Science | Vitroscreen
AUTHORS : Sahuc F MODELS : RHPE / RECONSTRUCTED HUMAN PIGMENTED EPIDERMIS APPLICATIONS : PIGMENTATION Reconstructed Human Pigmented Epidermis (RHPE): an in vitro model for the evaluation of melanogenesis. 2009 SOFW Magazine | SkinEthic
AUTHORS : Duché Daniel Ferraris C Labrie Fernand Leclaire J Luu-The Van Meunier Jean-Roch MODELS : EPISKIN APPLICATIONS : SKIN METABOLISM Expression profiles of phases 1 and 2 metabolizing enzymes in human skin and the reconstructed skin models Episkin and full thickness model from Episkin. 2009 J Steroid Biochem Mol Biol. 2009 Sep;116(3-5):178-86 | L'Oréal, Research & Innovation
AUTHORS : Bock U. Gamer AO Schafer-Korting M. MODELS : EPISKIN RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : PERCUTANEOUS ABSORPTION The use of reconstructed human epidermis for skin absorption testing: Results of the validation study. 2008 |
AUTHORS : Blumenberg M. de Brugerolle de Fraissinette A Gazel A Rosdy M MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : GENOTOXICITY Transcriptional profiling defines the effects of nickel in human epidermal keratinocytes. 2008 | SkinEthic
AUTHORS : CORDONE LORENZO DE CARO VIVIANA GIANDALIA GIULIA GIANNOLA LIBERO I. SIRAGUSA MARIA G. MODELS : HCE / HUMAN CORNEAL EPITHELIUM Ocular Gelling Microspheres: In Vitro Precorneal Retention Time and Drug Permeation Through Reconstituted Corneal Epithelium 2008 | SkinEthic
Development of a highly reproducible In Vitro Precorneal Retention Time and Drug Permeation Through Reconstituted Corneal Epithelium 2008 | SkinEthic
AUTHORS : Benech Kieffer F. Garrigues A. Gregoire S. Guy R.H. Ribaud C. MODELS : EPISKIN APPLICATIONS : PERCUTANEOUS ABSORPTION Prediction of chemical absorption into and through the skin 2008 British Journal of Dermatology | L'Oreal, Episkin, SkinEthic
AUTHORS : Challacombe Stephen J. Hube B. Kanzaria Priya Makwana Jagruti Moyes David L. Naglik Julian R. Rodgers Catherine A. Schaller M. Tappuni Anwar R. Tsichlaki Elina Weindl G Woodman Alexander J. MODELS : HOE / HUMAN ORAL EPITHELIUM HVE / HUMAN VAGINAL EPITHELIUM APPLICATIONS : GENOTOXICITY Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis 2008 Microbiology | St Thomas's Hospital, University of Tuebingen, Friedrich Schiller University Jena and Department of Microbial Pathogenicity Mechanisms