AUTORES : Alepee N. Bouez C Cotovio J Dakic V De Vecchi R Garcia C Mattos G Oliveira V Rigaudeau A-S MODELOS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APLICAÇÕES : PERCUTANEOUS ABSORPTION Permeability PHARMACOLOGY / TOXICOLOGY Skin corrosion Skin irritation SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS SKIN METABOLISM Implementation, availability and regulatory status of an OECD accepted Reconstructed Human Epidermis model in Brazil 2018 Vigil. sanit. debate 2018;6(1):64-71 | L'Oréal, EPISKIN
AUTORES : Aleksic Maja Kitteringham Neil R Naisbitt Dean J Olayanju Adedamola Sheffield David Spriggs Sandrine MODELOS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APLICAÇÕES : SKIN METABOLISM SKIN SENSITIZATION Effect of Repeated Daily Dosing with 2,4-Dinitrochlorobenzene on Glutathione Biosynthesis and Nrf2 Activation in Reconstructed Human Epidermis 2016 SOT Society of Toxicology | Unilever
AUTORES : Budimir N. Duché Daniel Eilstein Joan Hussler G. Lereaux Guillaume Wilkinson S. MODELOS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APLICAÇÕES : SKIN METABOLISM Comparison of xenobiotic metabolizing enzyme activities in ex vivo human skin and reconstructed human skin models from SkinEthic. 2014 Archives of Toxicology. 2014, March 22 | L'Oréal, Research & Innovation
AUTORES : Duché Daniel Eilstein Joan Garrigues A. Lereaux Guillaume Meunier Jean-Roch MODELOS : EPISKIN RHE / RECONSTRUCTED HUMAN EPIDERMIS APLICAÇÕES : SKIN METABOLISM Characterization of peroxidase activities in normal human skin compared with reconstructed human skin models 2013 Society of Toxicology (SOT) Annual meeting |
AUTORES : Alepee N. Cotovio J Duché Daniel Leclaire J Marrot L Ouedraogo G. Ovigne Jean-Marc Teissier M H MODELOS : EPISKIN HCE / HUMAN CORNEAL EPITHELIUM RHE / RECONSTRUCTED HUMAN EPIDERMIS APLICAÇÕES : GENOTOXICITY OCULAR IRRITATION OF CHEMICAL Phototoxicity Skin corrosion SKIN IRRITATION OF CHEMICALS SKIN METABOLISM L’Oréal commitment in the develo pment, evaluation and validation of screening and testing approaches contributing to the 3Rs 2011 | L'Oréal
AUTORES : Duché Daniel Eilstein Joan Leclaire J Lereaux Guillaume Meunier Jean-Roch APLICAÇÕES : SKIN METABOLISM Cutaneous Metabolism 2011 | L'Oreal
AUTORES : Duché Daniel Ferraris C Labrie Fernand Leclaire J Luu-The Van Meunier Jean-Roch MODELOS : EPISKIN APLICAÇÕES : SKIN METABOLISM Expression profiles of phases 1 and 2 metabolizing enzymes in human skin and the reconstructed skin models EpiskinTM and full thickness model from EpiskinTM 2009 Elsevier Journal of Steroid Biochemistry and Molecular Biology | L'Oréal, Episkin, SkinEthic
AUTORES : Duché Daniel Ferraris C Labrie Fernand Leclaire J Luu-The Van Meunier Jean-Roch MODELOS : EPISKIN APLICAÇÕES : SKIN METABOLISM Expression profiles of phases 1 and 2 metabolizing enzymes in human skin and the reconstructed skin models Episkin and full thickness model from Episkin. 2009 J Steroid Biochem Mol Biol. 2009 Sep;116(3-5):178-86 | L'Oréal, Research & Innovation
AUTORES : Cotovio J Leclaire J Roguet R MODELOS : EPISKIN APLICAÇÕES : PHARMACOLOGY / TOXICOLOGY SKIN METABOLISM Reconstructed skin for in vitro cutaneous pharmacotoxicology: Example of metabolic studies 1997 IN VITRO TOXICOL J MOL CELL TOXICOL. In Vitro Toxicology: Journal of Molecular and Cellular Toxicology 1997 ;10 (1):3-9 | R. Roguet, Life Sciences, L'Oreal Advanced Res. Laboratories, 1 Avenue E. Schueller, 93600 Aulnay sous Bois
AUTORES : Cotovio J Kremers P Leclaire J Pouradier Duteil X Roguet R Rougier A MODELOS : EPISKIN APLICAÇÕES : SKIN METABOLISM Cytochrome P450-dependent enzyme activities and testosterone metabolism in a reconstituted human epidermis 1995 In Vitro Toxicology: Journal of Molecular and Cellular Toxicology 1995 ;8 (1):97-104 | L'Oreal, Dept Central Securite Produits, 1, Avenue Eugene Schueller,93600 Aulnay sous Bois
AUTORES : Berthod F. Collombel C Damour O Shahabeddin L APLICAÇÕES : PHARMACOLOGY / TOXICOLOGY SKIN METABOLISM Characterization of skin reconstructed on a chitosan-cross-linked collagen-glycosaminoglycan matrix 1990 Skin Pharmacology 1990 ;3 (2):107-114 | Laboratoire de Substituts Cutanes (CNRS-URA 1341), Hopital Edouard Herriot, Pavillon 15, Place Arsonval, F-69437 Lyon
AUTORES : Bernard B. A. Jamoulle J C Lenoir M C Magdalou J Pham M A Shroot B Siest G APLICAÇÕES : PHARMACOLOGY / TOXICOLOGY SKIN METABOLISM Reconstituted epidermis: a novel model for the study of drug metabolism in human epidermis 1990 J Invest Dermatol 1990 ;94 (6):749-52 | Centre du Medicament Nancy, France.
AUTORES : Dubertret L APLICAÇÕES : PHARMACOLOGY / TOXICOLOGY SKIN METABOLISM Reconstruction of the human skin equivalent in vitro: a new tool for skin biology 1990 Skin Pharmacol 1990 ;3 (2):144-8 | Laboratoire de Dermatologie, INSERM U, Hopital St. Louis, Paris, France.